/* Header - Start */
:root {
  --text-active-color-menu-takeda-pro:  #9B288C;
}

.header-fixed {
  position: fixed;
  width: 100%;
  z-index: 50;
}

.section-main-navigation {
  position: fixed;
  width: 100%;
  z-index: 49;
  background-color: #FFFFFF;
  margin-top: 52px;
}

/*.section-main-navigation.for-desktop {*/
/*  border-bottom: 1px solid #E4E4E4;*/
/*}*/

.section-main-navigation.for-desktop:after {
  z-index: 8;
  content: '';
  height: 1px;
  width: 100%;
  position: absolute;
  background-color: #E4E4E4;
  bottom: 0;
}
.section-main-navigation.for-desktop {
  /*border-bottom: 1px solid #E4E4E4;*/
}

.region-main-navigation ul.menu-parent-level-1 > li.active-sub, .region-main-navigation ul.menu-parent-level-1 > li:hover {
  border-bottom: none;
}

.menu-parent-level-1 > li > a {
  padding: 29px 3px;
  position: relative;
  height: 102px;
  display: flex;
  align-items: center;
}

.menu-parent-level-1 > li > a:after {
  content: '';
  width: 100%;
  height: 4px;
  background-color: var(--primary-color);

  z-index: 11;
  display: none;
  position: absolute;
  bottom: 0;
}

.menu-parent-level-1 > li.active-sub >:after,
.menu-parent-level-1 > li:hover > a:after,
.menu-parent-level-1 > li > a.is-active:after,
.menu-parent-level-1 > li > a:hover:after {
  display: block;
}

.header-menu {
  position: relative;
}

.header-background {
  background: #9B288C;
}

header .menu--livtencity-cmv-header-menu ul li.menu-item:hover,
header .menu--livtencity-cmv-header-menu ul li.menu-item.active-sub {
  background: #7C2070;
}

header .header-navigation {
  display: flex;
  justify-content: space-between;
  width: 100%;
}

/*header .header-navigation > nav:first-of-type {*/
/*  !* width: 45%; *!*/
/*}*/

ul.menu-takeda-pro {
  display: none;
  position: absolute;
  top: 100%;
  z-index: 1;
  width: 100%;
  left: 0;
  padding: 25px 0;
  background: #FFFFFF;
  border: 1px #dddddd solid;
  border-top-width: 0;
  -webkit-box-shadow: 0px 0px 13px 4px rgb(0 0 0 / 10%);
  box-shadow: 0px 0px 13px 4px rgb(0 0 0 / 10%);
}

.menu-takeda-pro.menu-group__list > .menu-group__item {
  min-height: 125px;
  display: inline-block;
  vertical-align: top;
  width: auto;
  border-bottom: 0;
  border-right: 1px solid #ddd;
}


.menu-takeda-pro li a {
  padding: 0 14px;
  line-height: 40px;
  color: inherit;
}

.menu-takeda-pro li a:hover {
  text-decoration: none;
}

.menu-takeda-pro.menu-group__list > .menu-group__item > a {
  font-size: 17px;
  font-weight: bold;
}

.takeda-pro-pc .takeda-global {
  padding: 17px 22px;
  background: #F5F5F5;
  color: #FD0008;
  font-weight: 700;
  font-size: 14px;
  line-height: 130%;
  min-width: 135px;
}

.takeda-pro-pc .takeda-global a,
.takeda-pro-pc .takeda-global a:hover {
  color: #FD0008;
  text-decoration: none;
}

.takeda-pro-pc:hover .menu-takeda-pro {
  display: flex;
}

.takeda-pro-pc .takeda-global span:first-of-type {
  margin-right: 5px;
}


.takeda-global:hover {
  cursor: pointer;
}

.takeda-pro-pc .menu-group__item > a.is-active {
  color: #9b288c;
}

.header-navigation ul.menu-group__list.menu-takeda-pro.show {
  display: flex;
}

ul.menu.menu-takeda-pro {
  margin: 0;
  padding: 0;
  height: auto;
  color: black;
  text-indent: 0;
}

.menu-group__list {
  margin: 0;
  padding: 0;
  height: auto;
  color: black;
  text-indent: 0;
}

/*header .header-right {*/
/*  background: #F5F5F5;*/
/*  padding: 10px 22px;*/
/*  text-align: center;*/
/*  color: #FD0008;*/
/*  font-family: 'Gotham', sans-serif;*/
/*  font-style: normal;*/
/*  font-weight: 700;*/
/*  font-size: 14px;*/
/*  line-height: 30px;*/
/*}*/

/*header .header-right a,*/
/*header .header-right a:hover {*/
/*  color: #FD0008;*/
/*  text-decoration: none;*/
/*}*/

.for-desktop nav ul.menu,
.for-desktop .region-main-navigation ul.menu {
  margin: 0;
  display: flex;
}

.for-desktop .region-main-navigation ul.menu-parent-level-1 {
  justify-content: flex-end;
}

ul li.menu-item,
ul li.menu-group__item {
  list-style: none;
}

.header-navigation ul li.menu-item {
  font-family: 'Gotham', sans-serif;
  font-weight: 400;
  font-size: 12px;
  line-height: 120%;
  color: #FFFFFF;
  padding: 19px 22px;
}

.header-navigation ul li.menu-item a,
.header-navigation ul li.menu-item a:hover {
  color: #FFFFFF;
  text-decoration: none;
}

@media screen and (max-width: 768px) {
  .header-navigation ul li.menu-item {
    padding: 20.5px 20px;
  }
}

.main-navigation-right {
  position: initial;
}

.region-main-navigation .menu-item.has-submenu > ul {
  display: none;
}

.region-main-navigation ul li a:hover {
  text-decoration: none;
}

.region-main-navigation ul li.active-sub {
  border-bottom: 4px solid #9B288C;
}

/*.region-main-navigation ul li.menu-child-level-1.active-sub,*/
/*.region-main-navigation ul li.menu-child-level-1:hover {*/
/*  padding: 29px 3px 25px;*/
/*}*/


.region-main-navigation ul li.active-sub > a {
  color: #9B288C;
}

.region-main-navigation ul li a.is-active {
  color: #9B288C;
}

.region-main-navigation li.menu-child-level-1 {
  padding: 0 16px;
  text-align: center;
  display: flex;
  align-items: center;
}

.region-main-navigation li.menu-child-level-2 {
  padding: 17px 12px 19px 12px;
  margin-right: 20px;
}

.region-main-navigation ul.menu-parent-level-2 > li.active-sub,
.region-main-navigation ul.menu-parent-level-2 > li:hover {
  padding: 17px 12px 15px 12px;
}

.region-main-navigation li.menu-child-level-3 {
  padding: 17px 16px;
}

/*.region-main-navigation ul li.menu-child-level-3.active-sub {*/
/*  padding: 17px 16px 13px;*/
/*}*/

.region-main-navigation li.menu-child-level-1 a {
  font-family: 'Open Sans', sans-serif;
  font-style: normal;
  font-weight: 400;
  font-size: 16px;
  line-height: 140%;
  text-align: center;
  text-transform: uppercase;
  color: #666666;
}

.region-main-navigation li.menu-child-level-1:last-of-type {
  margin-right: 0;
}


.region-main-navigation ul.menu-parent-level-2 {
  width: 100%;
  background-color: #F2DBEF;
  position: absolute;
  z-index: 99;
  bottom: -62px;
  left: 0;
}

.menu-child-level-1.has-submenu:hover ul.menu-parent-level-2,
.menu-child-level-1.active-sub ul.menu-parent-level-2 {
  bottom: -59px;
}

.region-main-navigation ul.menu-parent-level-1 .menu-item.has-submenu:hover ul.menu-parent-level-2,
.region-main-navigation ul.menu-parent-level-2:hover {
  display: flex;
  z-index: 100;
}

/*.region-main-navigation ul.menu-parent-level-2 li.menu-child-level-2:first-child {*/
/*  margin-left: 20vw;*/
/*}*/

ul.menu-parent-level-2.active-sub > li > ul.menu-parent-level-3 li.menu-child-level-3 {
  border-bottom: none;
}

ul.menu-parent-level-2.active-sub > li > ul.menu-parent-level-3 li.menu-child-level-3 a {
  font-weight: 400;
  font-size: 14px;
  line-height: 130%;
  color: #9B288C;
}

ul.menu-parent-level-2.active-sub > li > ul.menu-parent-level-3 li.menu-child-level-3 a:hover,
ul.menu-parent-level-2.active-sub > li > ul.menu-parent-level-3 li.menu-child-level-3 a.is-active {
  font-weight: 700;
  color: #9B288C;
}

.region-main-navigation ul.menu-parent-level-3 {
  width: 100%;
  background-color: #F5F5F5;
  position: absolute;
  bottom: -58px;
  left: 0;
  background-image: linear-gradient(#dbd9d9, #F5F5F5);
}

.menu-child-level-2.has-submenu:hover ul.menu-parent-level-3,
.menu-child-level-2.active-sub ul.menu-parent-level-3 {
  bottom: -58px;
}

.region-main-navigation ul.menu-parent-level-2 .menu-item.has-submenu:hover ul.menu-parent-level-3,
.region-main-navigation ul.menu-parent-level-3:hover {
  display: flex!important;
  z-index: 1;
}

/*.region-main-navigation ul.menu-parent-level-3 li.menu-child-level-3:first-child {*/
/*  margin-left: 20vw;*/
/*}*/

.region-main-navigation li.menu-child-level-2 a {
  text-transform: uppercase;
  font-weight: 600;
  font-size: 16px;
  line-height: 140%;
  text-align: center;
  color: #666666;
}

.region-main-navigation li.menu-child-level-3 a {
  text-transform: unset;
  font-style: normal;
  font-weight: 400;
  font-size: 14px;
  line-height: 130%;
  text-align: center;
  color: #333333;
}

.global-header-sp .search-bar {
  text-align: center;
}

.global-header-sp > .navigation {
  display: flex;
  -webkit-box-pack: justify;
  -webkit-justify-content: space-between;
  -ms-flex-pack: justify;
  justify-content: space-between;
  padding: 8px 6px;
  align-items: center;
}

.global-header-sp {
  position: fixed;
  border-bottom: none;
  -webkit-box-shadow: 0 0 1px 0 #dddddd;
  box-shadow: 0 0 1px 0 #dddddd;
  background-color: #fff;
  z-index: 99;
  width: 100%;
  top: 0;
}

.global-header-sp .icon-menu:before,
.global-header-sp .icon-close:before {
  font-family: 'icomoon', sans-serif !important;
  speak: none;
  font-style: normal;
  font-weight: normal;
  font-variant: normal;
  text-transform: none;
  line-height: 1;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
}

.icon-menu:before,
.icon-close:before {
  width: 1em;
  height: 1em;
  font-size: 1.2em;
  color: #9B288C;
  margin-right: 0;
}

.global-header-sp .icon-menu:before {
  content: "\e901" !important;
}

.global-header-sp .icon-close:before {
  content: "\e900" !important;
}

.global-header-sp .menu-toggle.open .menu-open,
.global-header-sp .menu-toggle:not(.open) .menu-close {
  display: none;
}

.global-header-sp .menu-toggle:not(.open) + .menu-sp {
  display: none;
}

.global-header-sp .menu-toggle .menu-open span.hidden-sm-down,
.global-header-sp .menu-toggle .menu-close span.hidden-sm-down {
  display: none;
}

.global-header__item.hamburger .for-mobile > a {
  font-size: 2rem;
  padding: 12px;
}

.global-header__item.hamburger .for-mobile > a:hover {
  color: #9B288C;
}

.global-header__item.hamburger .for-mobile > div.menu-sp {
  font-family: 'Open Sans', sans-serif;
  font-style: normal;
  font-weight: 400;
  font-size: 16px;
  line-height: 140%;
  color: #666666;
  position: absolute;
  top: 100%;
  z-index: 1;
  width: 100%;
  left: 0;
  background-color: #ffffff;
  border-top: 1px solid #9B288C;
  overflow-y: scroll;
  max-height: 600px;
}

.menu-sp .menu-main-navigation {
  background-color: #ffffff;
}

.global-header-sp .global-header__item {
  width: 15%;
}

.global-header-sp .logo {
  width: 70%;
  text-align: center;
  display: table;
}

.global-header-sp .logo img {
  max-width: 182px;
}

.global-header-sp .search-button:before {
  vertical-align: middle;
  color: #9B288C;
  font-size: 24px;
}

.global-header-sp .menu-group__list {
  background: #ffffff;
  margin: 0;
  padding: 0;
  height: auto;
  color: #666666;
  text-indent: 0;
}

.global-header-sp .menu-main-navigation .menu-group__item {
  position: relative;
  margin: 0;
  width: 100%;
  font-size: 17px;
  color: inherit;
  text-indent: inherit;
  text-align: left;
  overflow: visible;
  display: block;
  z-index: inherit;
  /*border-bottom: 1px #D9D9D9 solid;*/
}

.global-header-sp ul.menu-group__list > .menu-group__item {
  padding-top: 12px;

}

.global-header-sp .menu-sp > ul.menu.menu-group__list > li.menu-group__item > a {
  text-transform: uppercase;
}

.global-header-sp .menu-main-navigation .menu-group__list li a,
.global-header-sp .menu-main-navigation .menu-group__list li span {
  padding-left: 32px;
  color: #666666;
  display: block;
}

.global-header-sp .menu-group__list li a,
.global-header-sp .menu-group__list li span {
  color: #666666;
}

.border-line {
  width: 90%;
  height: 1px;
  background-color: #D9D9D9;
  margin: 12px auto 0;
}

.global-header-sp .item-back-takeda-pro {
  font-weight: 400;
  color: #FD0008;
  padding: 24px 5.4vw 24px 18px;
  border-bottom: 1px solid #9B288C;
  display: flex;
  align-items: center;
  justify-content: space-between;
}

.global-header-sp .item-back-takeda-pro a,
.global-header-sp .item-back-takeda-pro a:hover {
  color: #FD0008;
  text-decoration: none;
}

.global-header-sp .item-menu-site {
  position: relative;
  padding: 12px 0 17px 20px;
  border-bottom: 1px #D9D9D9 solid;
  font-weight: 700;
  color: #9B288C;
}

.global-header-sp .item-menu-takeda-pro.item-menu-site {
  font-size: 16px;
  line-height: 132%;
  color: #FD0008;
  padding: 24px 18px;
}

.global-header-sp .menu-main-navigation .item-menu-site > button,
.global-header-sp .menu-main-navigation .menu-group__item button {
  position: absolute;
  top: 10px;
  right: 4.5%;
  margin: 8px;
  padding: 0;
  height: 12px;
  width: 12px;
  background: transparent;
  border: 2px #9B288C solid;
  border-color: #9B288C #9B288C transparent transparent;
  outline: none;
  cursor: pointer;
  -webkit-box-sizing: border-box;
  box-sizing: border-box;
  z-index: 2;
  -webkit-transform: rotate(45deg);
  transform: rotate(45deg);
  -webkit-transition-property: opacity, -webkit-transform;
  transition-property: opacity, -webkit-transform;
  transition-property: opacity, transform;
  transition-property: opacity, transform, -webkit-transform;
  -webkit-transition-duration: .25s;
  transition-duration: .25s;
}

.global-header-sp .item-menu-takeda-pro.item-menu-site > button {
  border: 2px #FD0008 solid;
  border-color: #FD0008 #FD0008 transparent transparent;
  top: 19px;
}

.global-header-sp .menu-takeda-pro li a {
  line-height: 140%;
}

.global-header-sp .menu-main-navigation .item-menu-site.menu-group__itemToggle > button,
.global-header-sp .menu-main-navigation .menu-group__itemToggle > button {
  opacity: 1;
  -webkit-transform: rotate(135deg);
  transform: rotate(135deg);
}


.global-header-sp .menu-group__item .menu-group__list {
  position: relative;
  -webkit-transition: max-height .25s, opacity .25s;
  transition: max-height .25s, opacity .25s;
  overflow: hidden;
  z-index: 1;
}
nav[class*="-header-menu"] {
  text-transform: uppercase;
}

.item-menu-site + ul.menu-group__list,
.item-menu-site +  ul.menu-group__list+ ul.menu-group-header,
.global-header-sp .menu-group__item .menu-group__list,
.global-header-sp .menu-group__item .menu-group-header {
  max-height: 0;
  opacity: 0;
}

.item-menu-site.menu-group__itemToggle + ul.menu-group__list,
.item-menu-site.menu-group__itemToggle + ul.menu-group__list + ul.menu-group-header,
.global-header-sp .menu-group__itemToggle > ul {
  max-height: 1000px !important;
  opacity: 1 !important;
  overflow: visible !important;
  z-index: 4 !important;
}

.item-back-takeda-pro > button {
  padding: 0;
  margin: 3px;
  height: 12px;
  width: 12px;
  background: transparent;
  border: 2px #FD0008 solid;
  border-color: #FD0008 #FD0008 transparent transparent;
  outline: none;
  cursor: pointer;
  -webkit-box-sizing: border-box;
  box-sizing: border-box;
  -webkit-transform: rotate(45deg);
  transform: rotate(45deg);
}

.global-header-sp .menu-main-navigation .menu-group__item.has-submenu.menu-group__itemToggle {
  padding-bottom: 0;
}

.global-header-sp .menu-main-navigation ul.menu-group-toggle > li.menu-group__item {
  background-color: #FFFFFF;
}

.global-header-sp .menu-main-navigation li.menu-group__item > ul.menu-group__list {
  background-color: #FDF4FC;
}

.menu-main-navigation ul.menu.menu-group__list li.menu-group__item.active-sub > a.is-active,
.menu-main-navigation .menu-group__item.has-submenu.menu-group__itemToggle > a {
  font-weight: 700;
  color: #9B288C;
}

.menu-group__item.has-submenu.menu-group__itemToggle > ul.menu-group__list li a.is-active + .border-line,
.menu-group__item.has-submenu.menu-group__itemToggle > ul.menu-group__list li:not(:last-child) > .border-line {
  background: #9B288C;
}

.menu-main-navigation .menu-group__item.has-submenu ul.menu-group__list li a {
  padding-left: 48px;
}

.menu-main-navigation .menu-group__item.has-submenu ul.menu-group__list li ul.menu-group__list li a {
  padding-left: 64px;
}


.menu-main-navigation ul.menu.menu-group__list li.menu-group__item.is-item-menu-active {
  background: #F2DBEF;
}


/* Takeda pro sp */

.takeda-pro-sp ul.menu-group__list {
  height: 100%;
}

.global-header-sp .takeda-pro-sp .menu-group__item {
  margin: 0;
  width: 100%;
  color: inherit;
  text-indent: inherit;
  text-align: left;
  overflow: visible;
  display: flex;
  justify-content: space-between;
  align-items: center;
}

.global-header-sp .takeda-pro-sp .menu-group__item > ul {
  position: absolute;
  top: 0;
  transform: translateX(100%);
  opacity: 0;
  visibility: hidden;
  width: 100%;
  height: 100%;
  transition: 0.6s;
  max-height: none!important;
}

.global-header-sp .takeda-pro-sp .menu-group__itemToggle > ul {
  max-height: 1000px !important;
  opacity: 1 !important;
  visibility: visible;
  overflow-y: scroll!important;
  overflow-x: hidden;
  z-index: 4 !important;
  transform: translateX(0%);
  left: 0;
  transition: 0.6s;
}

.global-header-sp .takeda-pro-sp .menu-group__item button {
  background: transparent;
  border: solid black;
  border-width: 0 3px 3px 0;
  display: inline-block;
  padding: 5px;
  transform: rotate(-45deg);
  -webkit-transform: rotate(-45deg);
  height: 10px;
  width: 10px;
  outline: none;
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li {
  padding: 20px 50px 20px 24px;
}

.takeda-pro-sp .menu-group__item.has-submenu ul li {
  padding: 17px 52px;
}

.takeda-pro-sp .menu-group__item.has-submenu ul li.parent-title + li {
  padding-top: 52px;
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list,
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li {
  padding-top: 32px;
}

.global-header-sp .takeda-pro-sp .item-close-menu {
  display: flex;
  justify-content: space-between;
  align-items: center;
  padding: 45px 36px 0 24px;
  z-index: 99;
}

.global-header-sp .takeda-pro-sp .item-close-menu .icon-close:before {
  font-size: 40px;
}

.menu-sp ul li.parent-title,
.menu-sp-takeda ul li.parent-title {
  margin-top: 36px;
  padding: 17px 32px;
  color: #333333;
  text-align: left;
}

a.back-to-menu-main:before,
.menu-sp ul li.parent-title:before,
.menu-sp-takeda ul li.parent-title:before {
  content: "";
  background: transparent;
  border: solid #333333;
  border-width: 0 3px 3px 0;
  display: inline-block;
  padding: 5px;
  transform: rotate(135deg);
  -webkit-transform: rotate(135deg);
  height: 10px;
  width: 10px;
  outline: none;
  margin-right: 10px;
}

.takeda-pro-sp a.menu-toggle {
  z-index: 99;
}

a.back-to-menu-main,
a.back-to-menu-main:hover {
  color: #666666;
  text-decoration: none;
}

/*Level 1 - Takeda pro*/
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.active-sub > span,
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.active-sub > a {
  color: var(--text-active-color-menu-takeda-pro);
  font-weight: 700;
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.active-sub > button {
  border: solid var(--text-active-color-menu-takeda-pro);
  border-width: 0 3px 3px 0;
}

/*Level 2 - Takeda pro*/
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.active-sub > a,
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.active-sub > span {
  color: var(--text-active-color-menu-takeda-pro);
  font-weight: 700;
}

.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li.active-sub > button {
  border: solid var(--text-active-color-menu-takeda-pro);
  border-width: 0 3px 3px 0;
}

/*Level 3 - Takeda pro*/
.global-header-sp .takeda-pro-sp > ul.menu-group__list > li.menu-group__item > ul.menu-group__list > li > ul > li a.is-active {
  color: var(--text-active-color-menu-takeda-pro);
  font-weight: 700;
}

.search-and-hcp-info {
  width: 43%;
  display: flex;
  justify-content: space-between;
  align-items: center;
  position: relative;
}

.search-and-hcp-info .mb-searchbar {
  position: absolute;
  display: none;
  top: 1px;
  left: -1px;
}

.search-and-hcp-info .mb-searchbar.showHideSearch {
  display: block;
}

.search-and-hcp-info .search-bar form .search__fieldset .search__input {
  padding: 15px 12px 16px 56px;
  font-weight: 400;
  font-size: 14px;
  line-height: 130%;
  color: #4F4F4F;
}

.search-and-hcp-info .search-button:before {
  vertical-align: middle;
  color: #FFFFFF;
  font-size: 24px;
}

.search-and-hcp-info .search-bar form .search__fieldset .search__submit {
  position: absolute;
  top: 50%;
  transform: translateY(-50%);
  padding: 0 0 0 22px;
}

.search-and-hcp-info .search-bar form .search__fieldset .search__submit:before {
  vertical-align: middle;
  color: #9B288C;
  font-size: 20px;
}

.search-and-hcp-info .menu-group__list li a {
  color: #666666;
}

.search-and-hcp-info .search__fieldset:hover,
.search-and-hcp-info .dropdown.icon:hover {
  cursor: pointer;
}

.search-and-hcp-info .dropdown.icon > svg {
  outline: none;
}

.menu-group__list li a:hover {
  text-decoration: none;
}

.search-and-hcp-info .dropdown.accessible-hover > .menu {
  top: 45px;
  right: 2px;
}

@media screen and (max-width: 1415px) {
  /*header .header-navigation > nav:first-of-type {*/
  /*  width: 47%;*/
  /*}*/

  .search-and-hcp-info {
    width: 38%;
  }

  .header-navigation ul li.menu-item {
    padding: 19px 15px;
  }
}

.global-header-sp .global-header__item.align-right {
  justify-content: center;
  display: flex;
  align-items: center;
}

.global-header-sp .search-bar form .search__fieldset .mb-searchbar {
  display: none;
  width: 100%;
  position: fixed;
  top: 83px;
  left: 0;
}

.global-header-sp .search-bar form .search__fieldset .showHideSearch {
  display: block;
}

.search-bar form .search__fieldset .search__input {
  display: inline-block;
  font-size: 1em;
  padding: 3px 0;
  border-style: solid;
  border-color: #cccccc;
  border-width: 0 0 1px 0;
  border-radius: 0;
  outline: 0;
  -webkit-box-flex: 1;
  -webkit-flex: 1 0 3em;
  -ms-flex: 1 0 3em;
  flex: 1 0 3em;
  -webkit-appearance: none;
}

.search-bar form .search__fieldset .search__submit {
  display: inline-block;
  border: 0;
  background: none;
  cursor: pointer;
  padding: 0 6px;
  position: absolute;
}

.search-bar form .search__fieldset .search__submit:before {
  vertical-align: middle;
  color: #c8c5c5;
  font-size: 24px;
}

.global-header-sp .search-bar form .search__fieldset .search__input {
  width: 100%;
  padding: 10px 30px 10px 7px;
  border-width: 1px 0;
}

.global-header-sp .search-bar form .search__fieldset .search__submit {
  right: 0;
  top: 50%;
  -webkit-transform: translateY(-50%);
  transform: translateY(-50%);
}

.dropdown.accessible-hover:before {
  position: relative;
}

.icon-profile-hcp:before {
  width: 1em;
  height: 1em;
  font-size: 28px;
  color: #9B288C;
  margin-left: 10px;
}

.dropdown .menu {
  display: none;
  position: absolute;
  top: 100%;
  left: auto;
  right: -1px;
  opacity: 0;
  border: 1px solid #bcbcbc;
  z-index: 2;
  -webkit-transition: max-height 0.5s ease-out;
  transition: max-height 0.5s ease-out;
}

.dropdown.accessible-hover > .menu {
  display: block;
  opacity: 1;
  padding: 0;
  right: 0;
  outline: 1px solid #dddddd;
  border: none;
  -webkit-box-shadow: 0px 1px 6px 0px rgb(0 0 0 / 20%);
  box-shadow: 0px 1px 6px 0px rgb(0 0 0 / 20%);
  background: #FFFFFF;
}

.dropdown.accessible-hover > .menu:before {
  border-bottom: 11px solid #ececec;
  border-left: 9px solid transparent;
  border-right: 7px solid transparent;
  position: absolute;
  content: "";
  width: 0;
  height: 0;
  right: 10px;
  top: -12px;
}

.dropdown.accessible-hover > .menu:after {
  border-bottom: 10px solid #FFFFFF;
  border-left: 7px solid transparent;
  border-right: 7px solid transparent;
  position: absolute;
  content: "";
  width: 0;
  height: 0;
  right: 10px;
  top: -10px;
}

.dropdown.accessible-hover > .menu .menu-group {
  width: 100% !important;
  background: #fff;
  font-size: 14px;
  min-width: 200px;
}

.dropdown.accessible-hover > .menu .menu-group:last-child {
  border-bottom: none;
}

.dropdown.accessible-hover .user-name-profile-hcp {
  padding: 12px;
  border-bottom: 1px solid #dddddd;
  display: block;
  vertical-align: middle;
  overflow: hidden;
  width: 100%;
  word-break: break-all;
  line-height: normal;
  color: #666666;
}

.dropdown.accessible-hover > .menu .menu-group .menu-group__list > .menu-group__item {
  width: 100%;
  border-right: 0;
  padding: 10px;
}

.global-header-sp .dropdown.accessible-hover ul li a {
  padding: 0;
}

.is-hidden {
  display: none;
}

.takeda-pro-sp {
  position: absolute;
  top: 0;
  left: 0;
  font-style: normal;
  font-weight: 700;
  font-size: 16px;
  line-height: 140%;
  color: #666666;
  z-index: 1;
  width: 100%;
  background-color: #ffffff;
  min-height: 800px;
  max-height: 1000px;
  transition: 0.4s;
  opacity: 0;
  transform: translateX(-110%);
  min-width: 250px;
}

.takeda-pro-sp.show {
  transform: translateX(0);
  opacity: 1;
  transition: 0.4s;
}

@media screen and (min-width: 993px) {
  .takeda-pro-sp,
  .for-mobile {
    display: none;
  }
}

@media screen and (max-width: 992px) {
  .takeda-pro-pc,
  .for-desktop {
    display: none;
  }

  .dropdown.accessible-hover > .menu {
    min-width: 200px;
    transform: translateX(-17px);
    top: 40px;
  }

}

/* Header - End */


.global-footer {
  overflow-x: hidden;
  background: #F5F5F5;
  padding: 28px 20px;
  border-left: 16px solid #FD0008;
  font-size: 17px;
}

footer {
  margin-top: 54px;
  overflow: hidden;
  background: #e6e7e8;
}

footer p {
  font-family: 'Gotham', sans-serif;
  font-size: 12px;
  font-weight: 400;
  margin-bottom: 20px;
  line-height: 16px;
}

.global-footer .container {
  padding-left: 10px;
  padding-right: 10px;
}


.global-footer .col-md-7,
.global-footer .col-md-8 {
  -webkit-flex: 0 0 59%;
  -ms-flex: 0 0 59%;
  -webkit-box-flex: 0;
  flex: 0 0 59%;
  max-width: 59%;
}


.global-footer ul {
  list-style: none;
  padding: 0;
}

.global-footer ul li {
  margin: 0;
  padding: 0;
  border: 0;
}

.global-footer .footer__social-wrap .footer__social .icon::before {
  margin-right: 0;
}

.global-footer .footer__social-wrap a,
.global-footer .footer__social-wrap a:hover,
.global-footer .footer__social-wrap a:focus {
  text-decoration: none !important;
  border: none !important;
  color: #000000;
  font-weight: 400 !important;
}

.global-footer .footer__worlwide .countryselector__url {
  display: inline-block;
  /*font-size: $font-size-base;*/
  margin: 0;
  text-transform: uppercase;
}

.global-footer .footer__worlwide .countryselector__url:hover, .global-footer .footer__worlwide .countryselector__url:focus {
  color: #ff0000;
}

.global-footer .footer__worlwide .icon__text {
  width: 1em;
  height: 1em;
  margin-right: 0.3em;
  position: relative;
  top: 0.15em;
  display: inline-block;
}

.global-footer .footer__worlwide .icon--red {
  fill: #ff0000;
}

@media screen and (max-width: 767px) {
  .global-footer {
    font-size: 12px;
    padding: 15px 0 15px 15px;
  }
}

.global-footer__nav-primary {
  /*border-bottom: 1px solid #aaa;*/
  margin-bottom: 20px;
}

.global-footer__nav-primary a {
  border-bottom: none;
}

@media screen and (max-width: 767px) {
  .global-footer__nav-primary {
    padding: 0;
  }
}

.global-footer ul.global-footer__nav-primary {
  padding: 0;
  margin-bottom: 0;
}

.global-footer .global-footer__nav-primary-item {
  width: auto;
  display: inline;
  padding-right: 16px;
}

.global-footer__nav-primary-item:before {
  content: '';
  border-left: 1px solid #000000;
  font-size: 9px;
  margin-right: 16px;
  color: #000000;
  position: relative;
  top: -2px;
}

.global-footer__nav-primary-item:first-of-type:before, .global-footer__nav-primary-item:first-child:before {
  content: '';
  display: none;
}

@media screen and (max-width: 767px) {
  .global-footer__nav-primary-item:nth-of-type(4):before {
    content: ' ';
    overflow: hidden;
    color: transparent;
    display: block;
  }
}

.global-footer__nav-primary-link {
  font-weight: 700;
  font-size: 16px;
  line-height: 140%;
  text-decoration-line: underline;
  color: #333333;
  white-space: nowrap;
}

.global-footer__nav-primary-link:hover {
  color: #ff0000;
  text-decoration: underline;
}

.global-footer__copyright {
  margin-top: 24px;
  font-style: normal;
  font-weight: 400;
  font-size: 12px;
  line-height: 130%;
  text-align: justify;
  color: #333333;
}

.global-footer__copyright p {
  margin: 0 0 10px 0;
}

.global-footer__copyright .discalimer {
  margin-bottom: 1em;
  font-family: "Open Sans Bold", "Helvetica Neue", Helvetica, Arial, sans-serif;
}

@media (max-width: 767px) {
  .global-footer__copyright-mobile {
    background: #ffffff;
    padding: 1rem;
    font-size: 15px;
  }
}

.global-footer .ratecontent {
  unicode-bidi: bidi-override;
  direction: rtl;
}

.global-footer .ratecontent > span {
  display: inline-block;
  position: relative;
  width: 1.1em;
  font-size: 1.5em;
}

.global-footer .ratecontent > span:hover:before,
.global-footer .ratecontent > span:hover ~ span:before {
  content: "\2605";
  position: absolute;
  color: red;
}


.global-footer .footer_logo_takeda {
  margin-right: 24px;
}

.global-footer .countryselector__url {
  display: none;
}

.global-footer .footer__social-wrap a {
  margin: 0 5px;
  font-size: 17px;
  text-decoration: none;
  display: inline-block;
}

.global-footer .footer__social-wrap a .hide {
  display: none;
}

.global-footer .footer__social-wrap a .footer__social__icon {
  width: 2em;
  height: 2em;
  display: inline-block;
  vertical-align: middle;
  position: relative;
  top: -0.1em;
  margin: 0 0 0 3px;
}

.global-footer .footer__social-wrap .icon--social {
  fill: #4B90B7;
}

.global-footer .footer__social-wrap .footer__social {
  display: flex;
  align-items: center;
  padding-top: 18px;
  font-size: 0;
}

.global-footer .footer__social__text {
  padding: 0 8px 0 0;
  font-weight: 700;
  font-size: 16px;
  line-height: 140%;
  color: #333333;
  display: inline-block;
}

/* Footer - End */


/*****************************/
/**** *** BACK TO TOP *** ***/
/***************************/
.back-to-top.btn.btn-secondary {
  position: fixed;
  font-weight: 700;
  font-size: 14px;
  line-height: 130%;
  color: #FFFFFF;
  z-index: 5;
  right: -300px;
  -webkit-transition: right 300ms ease-in-out;
  transition: right 300ms ease-in-out;
  will-change: right;
  width: 84px;
  height: 84px;
  background: #9B288C;
  border-radius: 1000px;
  display: flex;
  flex-direction: column;
  align-items: center;
  padding: 13px 19px;
  box-shadow: none;
  border: none;
  bottom: 39%;
}

.back-to-top.btn.btn-secondary:active,
.back-to-top.btn.btn-secondary:hover {
  background: #9B288C;
  color: #FFFFFF;
  box-shadow: none;
  border: none;
}

.back-to-top.btn.btn-secondary:before {
  content: '';
  display: inline-block;
  border: solid #FFCB03;
  border-width: 0 3px 3px 0;
  padding: 4px;
  width: 4px;
  transform: rotate(-135deg);
  -webkit-transform: rotate(-135deg);
  margin-bottom: 9px;
}

.back-to-top.btn.btn-secondary:after {
  top: 14px;
  left: 24px;
  font-size: 28px;
}

@media screen and (max-width: 992px) {
  .back-to-top.btn.btn-secondary:after {
    top: 15px;
    left: 13px;
    font-size: 24px;
  }
}

.back-to-top.btn.btn-secondary.show {
  right: 102px;
}
@media screen and (max-width: 540px) {
  .back-to-top.btn.btn-secondary.show {
    top: 40%;
  }
  .global-footer__nav-primary-item:before {
    display: none
  }
}
@media screen and (max-width: 1280px) {
  .back-to-top.btn.btn-secondary.show {
    right: 1em;
  }
}
.footer__wrapper {
  position: relative;
}
@media screen and (min-width: 1500px) {
  .back-to-top.btn.btn-secondary.show {
    right: calc(100% - 1194px - (100% - 1194px) / 2);
  }
}
/************************************/
.hd-external-link-overlay.d-none {
  display: none!important;
}
.hd-external-link-overlay {
  position: fixed;
  top: 0;
  left: 0;
  width: 100vw;
  height: 100vh;
  z-index: 999;
  background: rgba(0, 0, 0, 0.7);
  display: flex!important;
  align-items: center;
  justify-content: center;
}
.hd-external-link-overlay__wrapper {
  width: 85%;
  max-width: 800px;
}
.hd-external-link-overlay__close {
  width: 30px;
  height: 30px;
  background: url(../images/close-overlay.b90d6f08.svg);
  background-repeat: no-repeat;
  background-size: contain;
  background-position: 50%;
  margin-left: auto;
  cursor: pointer;
  position: absolute;
  top: 10px;
  right: 10px;
}
.hd-external-link-overlay__content {
  margin: 1em 0;
  background: #fff;
  padding: 2em 5em;
  max-height: 80vh;
  overflow-y: auto;
  text-align: center;
  position: relative;
}
.hd-external-link-overlay__title {
  font-size: 1.5em;
  font-weight: 600;
  margin: 1em 0;
}
.hd-external-link-overlay__copy {
  font-size: 1.1em;
}
.hd-external-link-overlay__controls {
  display: flex;
  align-items: center;
  justify-content: center;
  margin: 3em 0 1em 0;
}
.hd-external-link-overlay__controls--button {
  color: #fff;
  background: #4c4948;
  padding: 10px;
  border-radius: 20px;
  min-width: 130px;
  margin: 0 10px;
  cursor: pointer;
}
.hd-external-link-overlay__controls--button:hover,
.hd-external-link-overlay__controls--button:active,
.hd-external-link-overlay__controls--button.primary {
  background: #e10;
  color: #fff;
  text-decoration: none;
}
.hd-external-link-overlay p {
  margin-bottom: 0;
}
@media screen and (max-width: 767px) {
  .hd-external-link-overlay__content {
    padding: 2em 2em;
    font-size: 0.9em;
  }
  .hd-external-link-overlay__controls--button {
    margin: 10px 5px;
    min-width: 100px;
  }
}
@media (min-width: 992px) {
  .menu-child-level-1.has-submenu ul.menu-parent-level-2,
  .menu-child-level-2.has-submenu ul.menu-parent-level-3 {
    padding: 0 calc((100% - 1145px)/2);
  }
  .menu-parent-level-2.active-sub ,
  .menu-child-level-2.active-sub ul.menu-parent-level-3{
    display: flex!important;
  }
  nav[class*=main-navigation].contextual-region {
    position: initial!important;
  }
}

img.header-logo {
  max-width: 182px;
}